منابع مشابه
Generalized Bronchiectasis Associated with Deficiency of Cartilage
Bronchiectasis may occasionally affect almost the entire bronchial tree. Such changes can be the result either of developmental defects of the bronchial tree or of acquired inflammatory disease. For example, cystic lung and cystic bronchiectasis can result from both causes. The purpose of the present paper is to record five patients with a most unusual type of generalized bronchiectasis, and to...
متن کاملAuthor response—vitamin D deficiency and systemic inflammation in bronchiectasis.
Dr Charles Shee raises a further possible explanation for our finding of an association between vitamin D status and disease severity in bronchiectasis, that low vitamin D status represents a negative acute phase response to acute inflammation. Our study was cross-sectional and was unable to establish whether vitamin D deficiency is a cause or consequence of bronchiectasis. Possible explanation...
متن کاملImpaired pneumococcal antibody response in bronchiectasis of unknown aetiology.
As a defective anti-polysaccharide response can exist in the absence of an immunoglobulin deficiency, a series of 26 patients with bronchiectasis of unknown aetiology was vaccinated with a 23-valent pneumococcal polysaccharide vaccine. All patients suffered from recurrent respiratory tract infections. When measuring total antibody levels to pneumococcal serotypes 3, 4 and 9, a normal polysaccha...
متن کاملSpecific antibody response against the 23-valent pneumococcal vaccine in patients with alpha(1)-antitrypsin deficiency with and without bronchiectasis.
OBJECTIVE To assess the specific antibody response against polyvalent pneumococcal vaccine in patients with alpha(1)-antitrypsin deficiency (AATD) and respiratory infections. DESIGN AND PARTICIPANTS We investigated specific IgG, IgG1, and IgG2 antibody responses against the 23-valent antipneumococcal vaccine in 18 patients with AATD phenotype PiZZ, 9 of whom had bronchiectasis and 4 a history...
متن کاملTAP deficiency is also a cause of bronchiectasis.
We read with interest the recent bronchiectasis review by Whitters and Stockley. The authors provide a comprehensive overview of the changes in the immune response that might favour bacterial colonisation of the lower airways and in a second step initiate the vicious cycle leading to chronic inflammation and recurrent infections. Their description of the innate immune system in the lung include...
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ژورنال
عنوان ژورنال: European Respiratory Journal
سال: 2005
ISSN: 0903-1936,1399-3003
DOI: 10.1183/09031936.05.00027605